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Changzhou General Import and Export Corporation

Ace031, Ace 031, Ace 031 Price manufacturer / supplier in China, offering Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031, Peptides Raw Material Bodybuilding Supplement Legal Follistatin 344, Muscle Building Anabolic Steroid Hormones Dehydroisoandrosterone D H E a and so on.

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Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031

FOB Price: US $1 / Piece
Min. Order: 1 Piece
Min. Order FOB Price
1 Piece US $1/ Piece
Get Latest Price
Port: Shanghai, China
Production Capacity: 1000000kilograms/Week
Payment Terms: L/C, T/T, D/P, Western Union, Paypal, Money Gram, ESCROW

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Basic Info
  • Model NO.: CZG
  • Customized: Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • Spe: 1mg/Vial
  • MOQ: 1 Vial
  • Payment Method: Escrow, Western Union, Paypal, Tt, L/C.
  • Delivery Time: Within 3 Days After Payment
  • Export Markets: Global
  • Transport Package: Alumiuim Foil or as Customer′s Requirement
  • Origin: Jiangsu, China(Mainland)
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001, USP, BP
  • State: Solid
  • Name: Ace 031
  • Appearance: White Powder
  • Usage: Bodybuilding
  • Shipping Method: FedEx, DHL, EMS or by Sea
  • Place of Origin: Changzhou, Jiangsu
  • Trademark: CZG
  • Specification: USP
  • HS Code: 2937290090
Product Description

Ace031 Peptides Steroid ace Weight Loss 1mg Ace 031

Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031

Product Description:
ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.

ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases.

ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.
PEPTIDE INFORMATION


 Product Name:

ACVR2B / ACE-031 (untagged/tag free)

 Unit size:

1 mg/vial

 CAS NO.:

 

 Synonyms:

Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACE-031

 Sequence:

GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN

 Purity:

≥98% (HPLC)

 Physical State:

Lyophilized Powder

 Solubility:

Soluble in water or 1% acetic acid

 Storage:

Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.
 


Summary Results
 
-ACE-031 was well tolerated at all dose levels and demonstrated a linear pharmacokinetic profile with an average half-life ranging from 10-15 days
 
-Single doses of ACE-031 at 1 mg/kg and 3 mg/kg produced dose-dependent increases in lean body mass measured by dual energy X-ray absorptiometry (DXA) as early as day 15 that were sustained through day 57
 
-Subjects given single doses of placebo had a 0.2% decrease in lean body mass at day 57 compared to a 2.4% increase in subjects receiving 1 mg/kg ACE-031 and a 2.6% increase in subjects receiving 3 mg/kg ACE-031
 
-Subjects given single doses of placebo had a 0.2% decrease in muscle volume assessed by MRI at day 29 compared to a 3.5% increase in subjects receiving 1 mg/kg ACE-031 and 5% increase in subjects receiving 3 mg/kg ACE-031
 
-ACE-031 favorably affected biomarkers of fat mass (increased adiponectin and decreased leptin) and bone formation and resorption (increased bone-specific alkaline phosphatase (BSAP) and decreased C-terminal type 1 collagen telopeptide (CTX) at doses of 1 and 3 mg/kg
 
"ACE-031 holds great potential as a treatment for patients suffering from neuromuscular diseases such as muscular dystrophy and amyotrophic lateral sclerosis (ALS)," said John Knopf, Ph.D., Chief Executive Officer of Acceleron. "We are moving forward with great confidence and excitement with the ACE-031 program as well as our overall muscle franchise."
 
Muscle is increasingly recognized as central to many biological processes and plays a major role in human health. The loss of muscle mass and strength is ultimately directly related to the cause of death in neuromuscular diseases such as muscular dystrophy and amyotrophic lateral sclerosis. Severe muscle loss in cancer leads to serious complications and a poor prognosis. Muscle loss is a natural consequence of aging, similar to bone loss, resulting in decreased muscle strength (frailty), reduced mobility and an increased risk of a fall and broken bones. In metabolic diseases, an imbalance of diet, energy utilization and skeletal muscle leads to poor metabolic function. By increasing muscle mass there is a corresponding decrease in fat mass and improvements in metabolic function.
 
About ACE-031
 ACE-031, a soluble fusion protein based on the activin receptor type IIB (ActRIIB), is a biologic therapeutic that inhibits signaling through the ActRIIB receptor. By preventing signaling though ActRIIB, ACE-031 increases muscle mass and strength. In numerous and varied animal models of disease, ACE-031 significantly increased muscle mass and muscle strength. ACE-031, and a related molecule ACE-435, have shown encouraging preclinical results in animal models of age-related muscle loss, neuromuscular disease, cancer treatment-related muscle loss and metabolic diseases. ACE-031 is currently being studied in a Phase 1 multiple dose clinical trial in healthy volunteers. ACE-435 is expected to enter clinical trials in 2010.
 
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling 
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.

Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031

After-sales service:
1.We will ship the goods within 3days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.
2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
3.As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact me Immediately.
Factory price, pure injection, best credit.

 About us:
Changzhou General Import and Export Corporation. is a professional manufacturer and exporter that is concerned with the research,production and trading of pharmaceutical materials,including steriod series piperazidine series, pyrimidine series and other interrelated products. We are situated in Xinbei District,Changzhou City, Jiangsu Province, China. Changzhou General close to the Beijing-Shanghai Railway,Shanghai-Nanjing Express Way and Changzhou Airport. It is about an hour to Shanghai and Nanjing by high speed train.
Ace031 Peptides Steroid Ace Weight Loss 1mg Ace 031

Contact method:
Miss. Effy Hu
Sky-pe: live:effy_71
Whats-app: +8618861112317
  

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