Weight Loss Sarms Ibutamoren Mesylate Mk-677 Mk677
|FOB Price:||US $1 / g|
|Min. Order:||1 g|
|Min. Order||FOB Price|
|1 g||US $1/ g|
|Production Capacity:||1000 Kilograms Per Week|
|Transport Package:||Alumiuim Foil or as Customers Requirement|
|Payment Terms:||L/C, T/T, D/P, Western Union, Paypal, Money Gram, escrow and Bitcoin|
- Model NO.: Mk-677
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Mf: C27h36n4o5s.CH4o3s
- MW: 624.776
- Putity: 99% Min.
- Assay(HPLC): 99.59%
- Min Order Quantity: 1g
- Specification: CQC GMP IS9001 CNAS SGS
- HS Code: 3913900000
- Powder: Powder and Finished
- Certification: GMP, HSE, ISO 9001, USP, BP, GMP, USP
- State: Powder and Finished
- Name: Ibutamoren
- CAS No: 159752-10-0
- Appearance: Powder
- Brand: Czg
- Export Markets: Global
- Trademark: CZG
- Origin: Jiangsu, China(Mainland)
|Chemical Name||(R)-2-amino-N-[2-(1,2-dihydro-1-(methylsulfonyl) [3H-indole-3,49-piperidin]-19yl]-2-oxo-1-[(phenylmethoxy)-methyl]ethyl-2-methylpropanamide-monomethane sulfonate|
|Appearance||White to yellowish-white crystalline powder|
|Package||Super discreet package|
|Usage||SARM / Effective treatment of muscle wasting, obesity and osteoporosis / Bodybuilding|
What is MK-677?
Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels.
Such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
How does Ibutamoren work?
Ibutamoren MK-677 is a nonpeptide spiropiperidine and it is functionally indistinguishable in vitro as well as in vivo from the GHRP-6. However, ibutamoren stimulates GH release via a pituitary and hypothalamic receptors (not the same as the GH-delivering hormone receptors), and has the capacity to sustain GH plasma levels and IGF1 release without having affected endogenous cortisol.
Growth hormones pulse intensity could be elevated through 4 possible ways:
Growing GHRH release (growth hormones releasing hormone).
Increasing GHRH signaling in somatotrophs from the anterior anterior pituitary gland.
Reducing somatostatin release (somatostatin turns off GH release).
Suppressing somatostatin receptor signaling.
Ibutamoren MK-677 was shown to function through all of these four mechanisms. After ingestion, Growth Hormones (GH) was proven to improve dose dependently, at doses beginning at 5 mg (mgs) each day.
Dosages range from 10-40 mg per day. The most commonly used is 20-30 mg.
Clinical trials have demonstrated the efficacy of 25 mg to increase IGF-1. We take the supplement in one portion once a day, because of the 24-hour half-life.
Ibutamoren Mesylate COA:
|Characteristics||White to yellowish-white crystalline powder||conform|
|Melting point||32 ~ 37ºC||33~36ºC|
|Specific optical rotation||+77°~+82°||+79.3°|
|Loss on drying||≤0.5%||0.15%|
|Assay||97 ~ 103%||99.08%|
|Free heptanoic acid||≤0.2 %||0.10%|
|Residual solvents(GC)||Methanol ≤100ppm||Pass|
In a study on it's effects on catabolic states, a once daily oral dose of 25mgs was given to healthy young men subjected to short-term diet-induced nitrogen wasting. After 7 days of this dose, the subjects showed a sustained increase in serum concentration of IGF-1 and Growth Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting.
A study done for the treatment of osteoporosis and bone mineral density showed some increase in bone density, so there is a true impact on bone mineral density. This can help with injury recovery during your cycle.
Payment method: Escrow, Western Union, Paypal, moeny gram, BTC.
Shipping method: Fedex, DHL, EMS or by SEA
Delivery time: within 3days after payment, 7-10days to arrive.
The quality control process
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
Four steps: sampling, sample pretreatment, measuring and data processing.
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
1.We will ship the goods within 3days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.
2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
3.As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact me Immediately.
Factory price, pure injection, best credit.
Changzhou General Import and Export Corporation. is a professional manufacturer and exporter that is concerned with the research,production and trading of pharmaceutical materials,including steriod series piperazidine series, pyrimidine series and other interrelated products. We are situated in Xinbei District,Changzhou City, Jiangsu Province, China. Changzhou General close to the Beijing-Shanghai Railway,Shanghai-Nanjing Express Way and Changzhou Airport. It is about an hour to Shanghai and Nanjing by high speed train.
|1||Ibutamoren mesylate mk 677||159752-10-0|
|5||Ostarine MK-2866, Enobosarm||1202044-20-9/841205-47-8|
Offical website: http://www.czgpharmacy.com/.
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